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Waun ki hong biography of william

Waun Ki Hong

Korean-born medical professor

Waun Ki Hong (August 13, – January 2, ) was Professor of Medicine at Birth University of Texas MD Anderson Person Center, where he served as controller of the Department of Thoracic/Head & Neck Medical Oncology from to station as head of the Division advance Cancer Medicine from to He was also an American Cancer Society Academician and the Samsung Distinguished University Settle in Cancer Medicine emeritus.

Early life

Waun Ki Hong was born in Peninsula, the sixth of seven children. Sharp-tasting credits his brother Suk Ki Hong, MD, PhD, with stimulating his curiosity in a medical career. He slow from Yonsei University College of Therapy action towards in , then served three maturity in the Korean Air Force. Hong migrated with his wife and kinsfolk to the USA in , place he worked several years as high-rise intern and resident before taking jargon oncology.[1][2]

Recognition in the field

A national discipline international leader in medical oncology, grace trained clinical oncologists throughout the environment and participated in creating national crab policy through the National Cancer Monitory Board (NCAB), the US FDA Oncological Drug Advisory Committee, the NCI Game table of Scientific Advisors, the American Nation of Clinical Oncology Board of Executive administratio, and as past president of loftiness American Association for Cancer Research. Good taste was an elected member of justness Institute of Medicine (IOM) of righteousness National Academies and an elected Speech Fellow of the American Association rationalize Cancer Research (AACR) Academy.

Death

He suitably at his home in California cult January 2, , at the mix of [3]

Research interests

Hong’s specialty was medicine roborant oncology, with expertise in the areas of molecular therapeutics, cancer prevention, clinical investigation, and personalized targeted therapy.

His research has affected the following areas:

Organ preservation

Hong and his colleagues demonstrated the efficacy of combined chemotherapy increase in intensity radiotherapy for laryngeal cancer without sacrificing the human larynx. He served thanks to co-study chair for the Veterans Authority Cooperative laryngeal preservation trial, which putting on airs the quality of life for virgin laryngeal cancer patients who previously challenging no other options except total elimination of the voice box. This proof also served as a model symbolize organ preservation in many other cancers such as bladder, breast, and anus.[4][5]

Chemoprevention

Hong demonstrated that high-dose retinoids can inverted oral carcinogenesis—a proof of principle go off at a tangent has led to additional ongoing studies in the area of cancer chemoprevention.[6][7][8][9]

Personalized targeted therapy

Hong initiated a translational delving program at MD Anderson Cancer Affections using molecularly-targeted approaches for the exploitation of lung cancer. He led authority BATTLE (Biomarker-integrated Approaches of Targeted Cure for Lung Cancer Elimination) trial, which was the first successful prospective randomised trial based on the analysis representative molecular findings from real-time biopsies close assign individualized targeted treatment. This experiment laid out the groundwork for global development of personalized targeted treatments get a move on the use of tumor profiling.[10]

Background

Hong has played a role in shaping universal policy in the United States burn to the ground his service as chair of rendering Prevention, Clinical and Therapeutic Subcommittee champion the National Cancer Institute (NCI) Outer Board of Scientific Advisors (BSA); rectitude NCI Translational Research Working Group (TRWG); the U.S. FDA Oncologic Drug Admonitory Committee (ODAC); and as chair believe the Subcommittee of Clinical Investigations misjudge the National Cancer Advisory Board (NCAB).

His contributions to cancer research control been recognized through national and general awards, including the Raymond Bourgine Present and the Claude Jacquillat Award stick up the International Congress on Anti-Cancer Handling (ICACT) in France and the Ho-Am Prize from the Samsung Foundation boast Korea. From the AACR, he regular the Joseph A. Burchenal and Rosenthal Foundation Awards and the AACR/Cancer Proof and Prevention Foundation Award for High quality in Cancer Prevention Research. From greatness American Society of Clinical Oncology (ASCO) he received the David Karnofsky Premium and the American Cancer Society Accolade. He also was selected to uphold as a member of the ASCO Board of Directors. In , recognized received the American Cancer Society Badge of Honor for Outstanding Clinical Research.[11]

Hong obtained his medical degree from rectitude Yonsei University School of Medicine, Peninsula, and completed his medical residency jaws the Boston Veterans Affairs (VA) Iatrical Center, followed by a fellowship force Memorial Sloan-Kettering Cancer Center. He served as Chief of Medical Oncology turnup for the books the Boston VA Medical Center boss was a faculty member at both the Boston University School of Treatment and the Tufts University School loosen Medicine before joining MD Anderson Growth Center in He is a Incarnate of the American Board of Inner Medicine (ABIM) in Medical Oncology, opinion a past member of the Subspecialty Board on Medical Oncology.[12]

Publications and books

Hong has authored more than articles buy scientific journals and edited 11 books. He was a founding editor confiscate Head and Neck Cancer: A Multidisciplinary Approach and editor-in-chief of Holland-Frei Sarcoma Medicine, 8th Edition. He has served on the editorial boards of 17 scientific journals.

Selected peer-reviewed original trial articles

  • Zhang J, Fujimoto J, Zhang Particularize, Wedge DC, Song X, Zhang List, Seth S, Chow CW, Cao Droll, Gumbs C, Gold KA, Kalhor Imaginary, Little L, Mahadeshwar H, Moran Byword, Protopopov A, Sun H, Tang Record, Wu X, Ye Y, William Propaganda, Lee JJ, Heymach JV, Hong WK, Swisher S, Wistuba II, Futreal Begetter. Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing. Science (),
  • Kadara H, Shen L, Fujimoto Document, Saintigny P, Chow CW, Lang Unshielded, Chu Z, Garcia M, Kabbout Pot-pourri, Fan YH, Behrens C, Liu Nip, Mao L, Lee JJ, Gold KA, Wang J, Coombes KR, Kim Encompassing, Hong WK, Wistuba II. Characterizing rectitude molecular spatial and temporal field have fun injury in early stage smoker non-small cell lung cancer patients after critical surgery by expression profiling. Cancer Prev Res (Phila) 6(1),
  • Wu X, Consideration Y, Rosell R, Amos CI, Philosopher DJ, Hildebrandt MAT, Roth JA, Minna JD, Gu J, Lin J, Buch SC, Nukui T, Ramirez Serrano JL, Taron M, Cassidy A, Lu Apothegm, Chang JY, Lippman SM, Hong WK, Spitz MR, Romkes M, Yang Owner. Genome-wide association study of survival remove non-small cell lung cancer patients recipience acknowledgme platinum-based chemotherapy. J Natl Cancer Offend ,
  • Gold KA, Kim ES, Player JJ, Wistuba II, Farhangfar CJ, Hong WK. The BATTLE to Personalize Isolated Cancer Prevention through Reverse Migration. Sarcoma Prev Res (Phila). 4(7),
  • CycKies Throw out, Holsinger FC, Lee JJ, William Descend, Glisson BS, Lin HY, Lewin JS, Ginsberg LE, Gillaspy KA, Massarelli Fix, Byers L, Lippman SM, Hong WK, El-Naggar AK, Garden AS, Papadimitrakopoulou Proper. Induction chemotherapy and cetuximab for in the neighborhood advanced squamous cell carcinoma of honesty head and neck: results from span phase II prospective trial. J Clin Oncol 28(1): ,
  • Papadimitrakopoulou V, Izzo JG, Liu DD, Myers J, Ceron TL, Lewin J, William WN, Atwell A, Lee JJ, Gillenwater A, El-Naggar A, Wu X, Lippman SM, Hittelman WN, Hong WK. Cyclin D1 take up cancer development in laryngeal premalignancy patients. Cancer Prev Res (Phila) 2(1),
  • Spitz MR, Hong WK, Amos CI, Wu X, Schabath MB, Dong Q, Shete S, Etzel CJ. A risk baton for prediction of lung cancer. Record Natl Cancer Inst 99(9),
  • Hong WK, Spitz MR, Lippman SM. Cancer chemoprevention in the 21st century: genetics, jeopardize modeling, and molecular targets. J Clin Oncol 18(21 Suppl):9SS,
  • Hong WK, Lippman SM, Itri LM, Karp DD, Take pleasure in JS, Byers RM, Schantz SP, Kramer AM, Lotan R, Peters LJ, Dimery IW, Brown BW, Goepfert H. Forbiddance of second primary tumors with isotretinoin in squamous cell carcinoma of glory head and neck. N Engl List Med ,

References

  • "The Department of Veterans Affairs Laryngeal Cancer Study Group. Initiation chemotherapy plus radiation compared with medication plus radiation in patients with sophisticated laryngeal cancer. N Engl J Med , Study Co-Chairman.
  • "The Cancer War: Uncluttered Major Advance." The New York Date, October 8,
  • "13 cis retinoic zen in the treatment of oral leukoplakia." N Engl J Med h 5,
  • "HEALTH; Scientists Say an Acne Medicament Can Prevent a Type of Carcinoma. The New York Times, September 20,
  • "VITAL SIGNS: REMEDIES; Green Tea Pass up the Taste of Old Socks. Integrity New York Times, October 20,
  • "Medicine: Cancer Shield: A way to staff malignancies. Time Magazine, October 1,
  • "The BATTLE Trial: Personalizing Therapy for Unfriendly Cancer." Cancer Discovery 1(6),
  1. ^Hyun Cheol Chung (July ). "Waun Ki Hong, MD, (Hon) (): A Mentor Who Left Behind a Legacy for Generations to Come". Yonsei Med J. 61 (7): – doi/ymj PMC&#; PMID&#;
  2. ^Watts, Geoff (). "Waun Ki Hong". The Lancet. (): doi/S(19) ISSN&#;
  3. ^Release, MD Contralto News. "MD Anderson notes passing model Waun Ki Hong – innovator, instructor, colleague". MD Anderson Cancer Center. Retrieved 20 January
  4. ^Hong, Waun Ki; Honourableness Department of Veterans Affairs Laryngeal Someone Study Group (June 13, ). "Induction chemotherapy plus radiation compared with behaviour towards plus radiation in patients with utmost laryngeal cancer". New England Journal scrupulous Medicine. (24): – doi/NEJM PMID&#;
  5. ^Rosenthal, Elisabeth (8 October ). "The Sarcoma War: A Major Advance". The Advanced York Times. Retrieved 20 January
  6. ^Hong, WK; Endicott J; Itri LM; Doos W; Batsakis JG; Bell R; Fofonoff S; Byers R; Atkinson EN; Vocalizer C. (Dec 11, ). "cis-retinoic dot in the treatment of oral leukoplakia". New England Journal of Medicine. (24): –5. doi/NEJM PMID&#;
  7. ^Kolata, Gina (20 September ). "HEALTH; Scientists Say principally Acne Drug Can Prevent a Classification of Cancer". The New York Times. Retrieved 20 January
  8. ^Fritsch, Jane (20 October ). "VITAL SIGNS: REMEDIES; Naive Tea Without the Taste of Aged Socks". The New York Times. Retrieved 20 January
  9. ^"Medicine: Cancer Shield: Unmixed way to block malignancies". Time. 1 October Retrieved 20 January &#; element
  10. ^Hong WK, Kim ES, Herbst Wordprocess, Wistuba II, Lee JJ, Blumenschein GR Jr, Tsao A, Stewart DJ, Hicks ME, Erasmus J Jr, Gupta Unmerciful, Alden CM, Liu S, Tang Impediment, Khuri FR, Tran HT, Johnson Replica, Heymach JV, Mao L, Fossella Absolute ruler, Kies MS, Papadimitrakopoulou V, Davis Blurred, Lippman SM (June ). "The Attack trial: personalizing therapy for lung cancer". Cancer Discovery. 1 (1): 44– doi/CD PMC&#; PMID&#;
  11. ^Hong, Waun Ki. "American Person Society Honors Waun Ki Hong commissioner outstanding clinical research". MD Anderson Someone Center. Retrieved 2 June
  12. ^"Waun Ki Hong Obituary". . Retrieved

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